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A 2-part Phase 1/2 Open-label Trial Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of ODM-212 in Combination With Anti-cancer Therapy in Participants With Advanced Solid Tumours

Trial Profile

A 2-part Phase 1/2 Open-label Trial Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of ODM-212 in Combination With Anti-cancer Therapy in Participants With Advanced Solid Tumours

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 17 May 2026

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At a glance

  • Drugs ODM-212 (Primary) ; Gemcitabine; Ipilimumab; Nivolumab; Paclitaxel; Sotorasib
  • Indications Adenocarcinoma; Mesothelioma; Non-small cell lung cancer; Pancreatic cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms TEADCO
  • Sponsors Orion Pharma

Most Recent Events

  • 06 May 2026 New trial record
  • 23 Apr 2026 According to Orion Pharma media release, announced the initiation of a Phase 1b/2 basket trial evaluating ODM-212, a potential best-in-class, oral pan-TEAD inhibitor, in combination with standard of care treatments in Solid tumors..

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