A Randomized Phase 3, Multicenter, Open-Label Study Comparing TH-302 in Combination With Doxorubicin vs. Doxorubicin Alone in Subjects With Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma

Trial Profile

A Randomized Phase 3, Multicenter, Open-Label Study Comparing TH-302 in Combination With Doxorubicin vs. Doxorubicin Alone in Subjects With Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma

Completed
Phase of Trial: Phase III

Latest Information Update: 01 Aug 2017

At a glance

  • Drugs Evofosfamide (Primary) ; Doxorubicin
  • Indications Leiomyosarcoma; Liposarcoma; Nerve sheath neoplasms; Rhabdomyosarcoma; Soft tissue sarcoma; Synovial sarcoma
  • Focus Registrational; Therapeutic Use
  • Sponsors Threshold Pharmaceuticals
  • Most Recent Events

    • 02 Jun 2017 Results of post-hoc analysis presented at the 53rd Annual Meeting of the American Society of Clinical Oncology
    • 11 Oct 2016 Results presented at the 41st European Society for Medical Oncology Congress
    • 18 Aug 2016 The trial was discontinued in Poland (end date: 2016-05-10).
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