A Randomized, 2-Part, Crossover, Single Center Study to Evaluate Effect of Quinidine on the Pharmacokinetics of NKTR-118 and the Concomitant Effect of Quinidine and NKTR-118 on Morphine-induced Miosis.

Trial Profile

A Randomized, 2-Part, Crossover, Single Center Study to Evaluate Effect of Quinidine on the Pharmacokinetics of NKTR-118 and the Concomitant Effect of Quinidine and NKTR-118 on Morphine-induced Miosis.

Completed
Phase of Trial: Phase I

Latest Information Update: 06 Aug 2015

At a glance

  • Drugs Naloxegol (Primary) ; Quinidine (Primary) ; Morphine
  • Indications Arrhythmias; Constipation; Miosis; Pain
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors AstraZeneca
  • Most Recent Events

    • 06 Aug 2015 Results published in the Journal of Clinical Pharmacology.
    • 01 Sep 2012 Status changed from recruiting to completed as reported by ClinicalTrials.gov.
    • 19 Mar 2012 Status changed from not yet recruiting to recruiting as reported by ClinicalTrials.gov.
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