A Randomized, 2-Part, Crossover, Single Center Study to Evaluate Effect of Quinidine on the Pharmacokinetics of NKTR-118 and the Concomitant Effect of Quinidine and NKTR-118 on Morphine-induced Miosis.
Phase of Trial: Phase I
Latest Information Update: 06 Aug 2015
At a glance
- Drugs Naloxegol (Primary) ; Quinidine (Primary) ; Morphine
- Indications Arrhythmias; Constipation; Miosis; Pain
- Focus Adverse reactions; Pharmacokinetics
- Sponsors AstraZeneca
- 06 Aug 2015 Results published in the Journal of Clinical Pharmacology.
- 01 Sep 2012 Status changed from recruiting to completed as reported by ClinicalTrials.gov.
- 19 Mar 2012 Status changed from not yet recruiting to recruiting as reported by ClinicalTrials.gov.