Trial Profile
A Randomized, Double-Blind, Phase 3 Study of the Janus Kinase (JAK) 1/2 Inhibitor, Ruxolitinib, or Placebo in Combination With Capecitabine in Subjects With Advanced or Metastatic Adenocarcinoma of the Pancreas Who Have Failed or Are Intolerant to First-Line Chemotherapy (The JANUS 1 Study)
Status:
Discontinued
Phase of Trial:
Phase III
Latest Information Update: 06 Nov 2021
Price :
$35
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At a glance
- Drugs Ruxolitinib (Primary) ; Capecitabine
- Indications Adenocarcinoma; Pancreatic cancer
- Focus Registrational; Therapeutic Use
- Acronyms JANUS 1
- Sponsors Incyte Corporation
- 06 Mar 2018 Primary endpoint (Overall Survival (OS)) has not been met as per the results published in the Investigational New Drugs.
- 06 Mar 2018 Results assessing safety and efficacy published in the Investigational New Drugs
- 27 Jan 2017 This trial has been completed in Spain (end date: 12 Dec 2016).