A Phase I, Open-Label, Multicenter Study to Assess Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-tumor Activity of AZD4635, Both as Monotherapy and in Combination With Durvalumab in Patients With Advanced Solid Malignancies.

Trial Profile

A Phase I, Open-Label, Multicenter Study to Assess Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-tumor Activity of AZD4635, Both as Monotherapy and in Combination With Durvalumab in Patients With Advanced Solid Malignancies.

Recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Jul 2017

At a glance

  • Drugs AZD 4635 (Primary) ; Durvalumab (Primary)
  • Indications Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors AstraZeneca
  • Most Recent Events

    • 17 Jul 2017 Planned End Date changed from 12 Oct 2017 to 9 Nov 2017.
    • 17 Jul 2017 Planned primary completion date changed from 12 Oct 2017 to 9 Nov 2017.
    • 05 Apr 2017 According to a Heptares Therapeutics media release, the company expects to report results from this study around the end of the year 2017.
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