An Open-Label, Multicenter, Phase 1 Study With Expansion Cohorts of Ramucirumab or Necitumumab in Combination With Osimertinib in Patients With Advanced T790M-Positive EGFR-Mutant Non-Small Cell Lung Cancer After Progression on First-Line EGFR TKI Therapy

Trial Profile

An Open-Label, Multicenter, Phase 1 Study With Expansion Cohorts of Ramucirumab or Necitumumab in Combination With Osimertinib in Patients With Advanced T790M-Positive EGFR-Mutant Non-Small Cell Lung Cancer After Progression on First-Line EGFR TKI Therapy

Recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Aug 2017

At a glance

  • Drugs Necitumumab (Primary) ; Osimertinib (Primary) ; Ramucirumab (Primary)
  • Indications Non-small cell lung cancer
  • Focus Adverse reactions
  • Sponsors Eli Lilly
  • Most Recent Events

    • 22 Jun 2017 Planned End Date changed from 1 Apr 2020 to 1 May 2019.
    • 22 Jun 2017 Planned primary completion date changed from 8 May 2019 to 1 Oct 2017.
    • 03 Nov 2016 Status changed from not yet recruiting to recruiting.
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