Trial Profile
Phase 1, Open-label Dose-escalation and Dose-expansion Study to Evaluate the Safety, Expansion, Persistence and Clinical Activity of a Single Dose of UCART123 (Allogeneic Engineered T-cells Expressing Anti-CD123 Chimeric Antigen Receptor), Administered in Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
Status:
Discontinued
Phase of Trial:
Phase I
Latest Information Update: 05 Nov 2021
Price :
$35
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At a glance
- Drugs UCART 123 (Primary)
- Indications Blastic plasmacytoid dendritic cell neoplasm
- Focus Adverse reactions; First in man
- Acronyms ABC123
- Sponsors Cellectis
- 29 Jul 2019 Status changed from recruiting to discontinued.
- 13 Nov 2017 According to a Cellectis media release, In connection with the lifting of the clinical hold, Company agreed with the FDA to certain revisions to be implemented in protocol.
- 06 Nov 2017 According to a Cellectis media release, the US FDA has has lifted the clinical hold on Phase 1 trials of UCART123 in acute myeloid leukemia (AML) and blastic plasmacytoid dendritic cell neoplasm (BPDCN).