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Adjuvant immunotherapy after salvage surgery in head and neck squamous cell carcinoma : phase 2 trial evaluating the efficacy and the toxicity of nivolumab alone, and of the combination nivolumab and ipilimumab

Trial Profile

Adjuvant immunotherapy after salvage surgery in head and neck squamous cell carcinoma : phase 2 trial evaluating the efficacy and the toxicity of nivolumab alone, and of the combination nivolumab and ipilimumab

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 15 May 2025

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At a glance

  • Drugs Ipilimumab (Primary) ; Nivolumab (Primary)
  • Indications Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Mouth neoplasm; Oropharyngeal cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms ADJORL1

Most Recent Events

  • 08 May 2025 Planned End Date changed from 1 May 2026 to 1 Nov 2027.
  • 08 May 2025 Planned primary completion date changed from 1 May 2026 to 1 Nov 2027.
  • 27 Mar 2024 Planned End Date changed from 1 Feb 2024 to 1 May 2026.

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