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A Multicenter, Randomized, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Phase 3 Study to Evaluate the Efficacy and Safety of Benralizumab 100 mg in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent COPD Exacerbations and Elevated Peripheral Blood Eosinophils (RESOLUTE)

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Trial Profile

A Multicenter, Randomized, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Phase 3 Study to Evaluate the Efficacy and Safety of Benralizumab 100 mg in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent COPD Exacerbations and Elevated Peripheral Blood Eosinophils (RESOLUTE)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 24 Sep 2025

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At a glance

  • Drugs Benralizumab (Primary)
  • Indications Chronic obstructive pulmonary disease
  • Focus Registrational; Therapeutic Use
  • Acronyms RESOLUTE
  • Sponsors AstraZeneca; AstraZeneca AB; AstraZeneca KK

Most Recent Events

  • 19 Aug 2025 Status changed from active, no longer recruiting to completed.
  • 14 Apr 2025 Planned End Date changed from 21 Aug 2025 to 8 Aug 2025.
  • 14 Apr 2025 Planned primary completion date changed from 21 Aug 2025 to 8 Aug 2025.

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