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Thapsigargin

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Drug Profile

Thapsigargin

Latest Information Update: 16 Jul 2016

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At a glance

  • Originator Unknown
  • Developer LC Chemical Corporation; Merck & Co; Nonindustrial source; Unknown
  • Class Anti-ischaemics; Antiarrhythmics; Cardiotonics; Lactones; Sesquiterpenes; Small molecules
  • Mechanism of Action Calcium channel antagonists; Calcium-transporting ATPase inhibitors; JNK mitogen-activated protein kinase modulators; P-glycoprotein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No

Highest Development Phases

  • No development reported Arrhythmias; Cancer; Heart failure; Ischaemic heart disorders

Most Recent Events

  • 16 Jul 2016 No recent reports of development identified for preclinical development in Cancer in Singapore
  • 19 Nov 2009 Preclinical trials in Cancer in Singapore (unspecified route)
  • 19 Nov 2009 Pharmacodynamics data from a preclinical trial in Cancer presented at the 21st AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics (AACR-NCI-EORTC-2009)

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