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VQW 765

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Drug Profile

VQW 765

Alternative Names: AQW-051; JQH481R778; VQW-765

Latest Information Update: 12 Nov 2025

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At a glance

  • Originator Novartis
  • Developer Novartis; Vanda Pharmaceuticals
  • Class Antipsychotics; Anxiolytics; Azabicyclo compounds; Behavioural disorder therapies; Bridged bicyclo compounds; Ethers; Nootropics; Pyridines; Small molecules; Toluenes
  • Mechanism of Action Alpha7 nicotinic acetylcholine receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Social phobia
  • Phase II Cognition disorders; Drug-induced dyskinesia; Phobic disorders

Most Recent Events

  • 12 Nov 2025 Chemical structure information added.
  • 22 Sep 2025 Phase-III clinical trials in Social phobia in USA (PO) (NCT07221578)
  • 02 Dec 2022 Efficacy data from a phase II trial in Phobic disorders released by Vanda Pharmaceuticals

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