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Utomilumab - Pfizer

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Drug Profile

Utomilumab - Pfizer

Alternative Names: PF-05082566; PF-2566; PF-5082566

Latest Information Update: 19 Jan 2026

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At a glance

  • Originator Pfizer
  • Developer Immatics US; Kite Pharma; Kyowa Kirin; M. D. Anderson Cancer Center; Pfizer
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action CD137 antigen agonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Breast cancer; Oropharyngeal cancer
  • Phase I/II Diffuse large B cell lymphoma; Solid tumours; Squamous cell cancer
  • No development reported B-cell lymphoma; Colorectal cancer; Follicular lymphoma; Non-Hodgkin's lymphoma; Ovarian cancer

Most Recent Events

  • 30 Dec 2025 Pfizer and M.D. Anderson Cancer Center completes a phase I trials in Colorectal cancer (Combination therapy, Late-stage disease, Metastatic disease, In adolescents, In adults, In the elderly) in USA (IV) (NCT03290937)
  • 28 Aug 2025 No recent reports of development identified for phase-I development in Follicular lymphoma(First-line therapy) in USA (IV)
  • 28 Aug 2025 No recent reports of development identified for phase-I development in Follicular lymphoma(Second-line therapy or greater) in USA (IV)

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