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Enitociclib - Bayer

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Drug Profile

Enitociclib - Bayer

Alternative Names: BAY-1251152; VIP-152

Latest Information Update: 15 Jul 2026

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At a glance

  • Originator Bayer
  • Class Antineoplastics; Fluorinated hydrocarbons; Organic sulfur compounds; Phenyl ethers; Pyridines; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 9 inhibitors; Positive transcriptional elongation factor B inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Diffuse large B cell lymphoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Haematological malignancies; Non-Hodgkin's lymphoma
  • Preclinical Multiple myeloma; Pancreatic cancer
  • No development reported Chronic lymphocytic leukaemia; Richter's syndrome; Solid tumours

Most Recent Events

  • 22 Apr 2026 Preclinical trials in Pancreatic cancer in USA (unspecified route), prior to April 2026
  • 22 Apr 2026 Adverse event and pharmacodynamics data from preclinical studies in Pancreatic cancer presented at the 117th Annual Meeting of the American Association for Cancer Research (AACR-2026)
  • 28 Jan 2026 No recent reports of development identified for phase-I development in Chronic-lymphocytic-leukaemia(Combination therapy) in Unknown (IV, Infusion)

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