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H3B 6545

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Drug Profile

H3B 6545

Alternative Names: H3B-6545

Latest Information Update: 28 Aug 2025

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At a glance

  • Originator H3 Biomedicine
  • Developer Eisai Co Ltd; H3 Biomedicine
  • Class Amides; Amines; Antineoplastics; Fluorocarbons; Indazoles; Pyridines; Small molecules
  • Mechanism of Action Estrogen receptor alpha antagonist
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II HER2 negative breast cancer

Most Recent Events

  • 28 Aug 2025 No recent reports of development identified for phase-I development in HER2-negative-breast-cancer(Combination therapy, Late-stage disease, Metastatic disease, Recurrent, Second-line therapy or greater) in European Union (PO)
  • 28 Aug 2025 No recent reports of development identified for phase-I development in HER2-negative-breast-cancer(Combination therapy, Late-stage disease, Metastatic disease, Recurrent, Second-line therapy or greater) in United Kingdom (PO)
  • 28 Aug 2025 No recent reports of development identified for phase-I development in HER2-negative-breast-cancer(Combination therapy, Late-stage disease, Metastatic disease, Recurrent, Second-line therapy or greater) in USA (PO)

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