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Culmerciclib - Chia Tai Tianqing Pharmaceutical Group

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Drug Profile

Culmerciclib - Chia Tai Tianqing Pharmaceutical Group

Alternative Names: Saitanxin; TQB-3616

Latest Information Update: 03 Jul 2026

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At a glance

  • Originator Chia Tai Tianqing Pharmaceutical Group
  • Class 2 ring heterocyclic compounds; Alkanes; Amines; Antineoplastics; Benzene derivatives; Fluorinated hydrocarbons; Indazoles; Piperazines; Pyrazoles; Pyridines; Pyrimidines; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 4 inhibitors; Cyclin-dependent kinase 6 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered HER2 negative breast cancer
  • Phase II Liposarcoma; Lung cancer

Most Recent Events

  • 06 Jun 2026 Fudan University initiates a phase II trial in HER2 negative breast cancer (Late stage disease, Metastatic disease, First line therapy, combination therapy) in China (PO) (NCT07666555)
  • 06 Jun 2026 Fudan University initiates a phase II trial in HER2 negative breast cancer (Late stage disease, Metastatic disease, Second line therapy or greater, combination therapy) in China (PO) (NCT07666555)
  • 02 Jun 2026 Efficacy and adverse events data from the phase II trial in HER2-negative breast cancer trial presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2026)

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