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Pevifoscorvir sodium - Aligos Therapeutics

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Drug Profile

Pevifoscorvir sodium - Aligos Therapeutics

Alternative Names: ALG-000184

Latest Information Update: 24 Apr 2026

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At a glance

  • Originator Aligos Therapeutics
  • Class Alkynes; Amides; Antivirals; Cyclic ethers; Fluorobenzenes; Hepatoprotectants; Ketones; Nitriles; Pyrroles; Small molecules
  • Mechanism of Action Capsid protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hepatitis B

Most Recent Events

  • 16 Apr 2026 Aligos Therapeutics enters into an exclusive license agreement to develop and commercialize pevifoscorvir sodium with Xiamen Amoytop Biotech for chronic hepatitis B virus infection in China, Taiwan, Hong Kong, and Macau
  • 20 Feb 2026 Aligos Therapeutics initiates a phase I trial for Hepatitis B in USA (PO) (NCT07342881)
  • 30 Jan 2026 Phase-I clinical trials in Hepatitis B in USA (PO) (NCT07342868)

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