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BT 001

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Drug Profile

BT 001

Alternative Names: Antibody-encoding oncolytic virus - BioInvent International/Transgene; BT-001; TG-6030; TG-6030 - Bioinvent International/Transgene; VV-α-CTLA-4

Latest Information Update: 06 Nov 2025

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At a glance

  • Originator BioInvent International; Transgene
  • Class Antibodies; Antineoplastics; Cytokines; Gene therapies; Immunotherapies; Monoclonal antibodies; Oncolytic viruses
  • Mechanism of Action Cell death stimulants; Cytotoxic T-lymphocyte antigen 4 inhibitors; Granulocyte-macrophage colony-stimulating factor expression stimulants; Immunologic cytotoxicity; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 20 Oct 2025 Updated efficacy and adverse events data from a phase I/II trial in Solid tumors released by BioInvent and Transgene
  • 13 Sep 2024 Preliminary efficacy and adverse events data from a phase I/II trial in Solid tumours presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)
  • 25 May 2023 Adverse events and efficacy data from a phase I/II trial in Solid tumors released by BioInvent and Transgene

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