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ABL 104

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Drug Profile

ABL 104

Alternative Names: ABL-104; YH-32364

Latest Information Update: 30 Oct 2025

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At a glance

  • Originator ABL Bio
  • Developer ABL Bio; Yuhan
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action CD137 antigen agonists; Epidermal growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Gastric cancer

Most Recent Events

  • 30 Oct 2025 Preclinical development is ongoing in Gastric cancer in South Korea (Parenteral) (ABL Bio pipeline, October 2025)
  • 16 May 2025 Yuhan Corporation plans a phase I/II trial for Solid tumours (Late-stage disease, Metastatic disease) in South Korea (IV, Infusion) in June 2025 (NCT06975410)
  • 25 Apr 2025 Pharmacodynamics and adverse events data from a preclinical study in Cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)

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