Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

HBI 2376

Next Previous
Drug Profile

HBI 2376

Alternative Names: GH-21; HBI-2376

Latest Information Update: 16 Sep 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Suzhou Genhouse Bio
  • Developer HUYA Bioscience International; Suzhou Genhouse Bio
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Protein tyrosine phosphatase non-receptor type 11 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Solid tumours
  • Phase I/II Non-small cell lung cancer

Most Recent Events

  • 16 Sep 2025 Drug is still in phase-I development in Solid-tumours (Late-stage disease, Metastatic disease) in China (PO, Capsule) (NCT05183243)
  • 16 Sep 2025 HBI 2376 is still in phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO)
  • 13 Aug 2025 Chia Tai Tianqing Pharmaceutical Group enters into clinical collaboration with Genhouse Bio, before August 2025 (Suzhou GenHouse Bio pipeline, August 2025)

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top