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Research programme: Phenethylamines and tryptamines derivatives - Cybin

Drug Profile

Research programme: Phenethylamines and tryptamines derivatives - Cybin

Alternative Names: CYB-005

Latest Information Update: 18 Nov 2025

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At a glance

  • Originator Cybin
  • Class Behavioural disorder therapies; Phenethylamines; Small molecules; Tryptamines
  • Mechanism of Action Serotonin 5-HT2A receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical CNS disorders
  • Discontinued Psychiatric disorders

Most Recent Events

  • 18 Nov 2025 Discontinued for Psychiatric disorders (Treatment-resistant) in Canada (unspecified route) prior to November 2025 (Cybin pipeline, November 2025)
  • 18 Nov 2025 Preclinical trials in CNS disorders in Canada (unspecified route) prior to November 2025 (Cybin pipeline, November 2025)
  • 06 Nov 2025 Research development for Psychiatric disorders (Treatment-resistant) is ongoing in Canada

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