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BIIB 115

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Drug Profile

BIIB 115

Alternative Names: BIIB-115; ION-306

Latest Information Update: 20 Oct 2022

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At a glance

  • Originator Ionis Pharmaceuticals
  • Developer Biogen; Ionis Pharmaceuticals
  • Class Antisense oligonucleotides
  • Mechanism of Action RNA interference; Survival of motor neuron 2 protein expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Spinal muscular atrophy

Most Recent Events

  • 12 Oct 2022 Biogen plans a phase I trial in Spinal muscular atrophy (In vounteers) (Intrathecal, Injection) in October 2022 (NCT05575011) (EudraCT2022-000956-12)
  • 10 Oct 2022 Phase-I clinical trials in Spinal muscular atrophy (In volunteers) in Netherlands (Intrathecal) (NCT05575011) (EudraCT2022-000956-12)
  • 04 Jan 2022 BIIB 115 licensed to Biogen worldwide for the treatment of spinal muscular atrophy

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