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VTX 3232

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Drug Profile

VTX 3232

Alternative Names: LY-5625573; NLRP3 inflammasome inhibitors - Ventyx Biosciences; VTX-3232

Latest Information Update: 14 Oct 2026

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At a glance

  • Originator Ventyx Biosciences
  • Class Anti-inflammatories; Antidementias; Antiparkinsonians; Neuroprotectants; Obesity therapies; Small molecules
  • Mechanism of Action NLRP3 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Inflammation; Obesity; Parkinson's disease
  • No development reported Neurodegenerative disorders

Most Recent Events

  • 30 Sep 2026 Eli Lilly and Company plans a phase I trial for Inflammation (In volunteers) in USA and Singapore (PO, Tablet) in September 2026 (NCT07867340)
  • 25 Aug 2026 LY 5625573 added to synonym (Eli Lilly and Company pipeline, August 2026)
  • 28 Jul 2026 No recent reports of development identified for phase-I development in Neurodegenerative-disorders(In volunteers) in Unknown (PO)

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