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VTX 3232

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Drug Profile

VTX 3232

Alternative Names: NLRP3 inflammasome inhibitors - Ventyx Biosciences; VTX-3232

Latest Information Update: 03 Nov 2025

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At a glance

  • Originator Ventyx Biosciences
  • Class Antidementias; Antiparkinsonians; Neuroprotectants; Obesity therapies; Small molecules
  • Mechanism of Action NLRP3 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Obesity; Parkinson's disease
  • Phase I Neurodegenerative disorders

Most Recent Events

  • 22 Oct 2025 Efficacy and adverse events data from a phase II trial in Obesity released by Zomagen Biosciences
  • 07 Aug 2025 Pharmacodynamics data from phase IIa clinical trials in Parkinson's disease released by Ventyx Biosciences
  • 17 Jun 2025 Pharmacokinetics, pharmacodynamics and adverse events data from phase IIa clinical trials in Parkinson's disease released by Ventyx Biosciences

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