Zoldonrasib - REVOLUTION Medicines
Alternative Names: RMC-9805Latest Information Update: 16 Jan 2026
At a glance
- Originator REVOLUTION Medicines
- Class Acetamides; Antineoplastics; Azabicyclo compounds; Aziridines; Cyclopentanes; Esters; Fluorinated hydrocarbons; Heterocyclic compounds with 4 or more rings; Indoles; Ketones; Methyl ethers; Morpholines; Piperazines; Pyridazines; Pyridines; Small molecules; Spiro compounds
- Mechanism of Action KRAS protein inhibitors
-
Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I/II Adenocarcinoma; Non-small cell lung cancer
- Preclinical Colorectal cancer
Most Recent Events
- 08 Jan 2026 Zoldonrasib - REVOLUTION Medicines receives Breakthrough Therapy status for Non-small cell lung cancer (Second-line therapy or greater) in USA
- 06 Nov 2025 Tango Therapeutics plans registrational trial in Adenocarcinoma (Combination therapy, First-line therapy) in the first half of 2026
- 17 Sep 2025 Chemical structure information added.