Drug Profile

PMN 267

Alternative Names: PMN-267; TDP43 targeting antibody - ProMIS Neurosciences

Latest Information Update: 28 Apr 2026

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At a glance

Originator ProMIS Neurosciences
Class Antidementias; Monoclonal antibodies
Mechanism of Action TDP-43 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Preclinical Dementia; Frontotemporal dementia
No development reported Amyotrophic lateral sclerosis

Most Recent Events

28 Apr 2026 No recent reports of development identified for preclinical development in Amyotrophic-lateral-sclerosis in Canada (Parenteral)
12 Nov 2025 ProMIS Neurosciences plans to initiate IND-enabling studies
14 Oct 2025 Preclinical trials in Dementia in Canada (Parenteral) (ProMIS Neurosciences pipeline, October 2025)

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