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AG 73305

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Drug Profile

AG 73305

Alternative Names: AG-73305; AM-305; Anti-VEGF/disintegrin fusion protein - Allgenesis Biotherapeutics

Latest Information Update: 10 Nov 2023

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At a glance

  • Originator Allgenesis Biotherapeutics
  • Class Anti-inflammatories; Antifibrotics; Disintegrins; Eye disorder therapies; Immunoglobulin Fc fragments; Recombinant fusion proteins
  • Mechanism of Action Integrin inhibitors; Vascular endothelial growth factors inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Diabetic macular oedema
  • Preclinical Retinal disorders; Retinal vein occlusion; Wet age-related macular degeneration

Most Recent Events

  • 08 Nov 2023 Updated preliminary safety and efficacy data from the phase IIa in Diabetic macular edema was released by Allgenesis Biotherpaeutics
  • 25 May 2023 Adverse events and efficacy data from a phase IIa trial in diabetic macular edema released by AffaMed Therapeutics
  • 09 Jun 2022 Phase-II clinical trials in Diabetic macular oedema (In adults, In the elderly) in USA (Intravitreous) (NCT05301751)

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