Drug Profile

Research programme: IL18 heterodimeric Fc-fusion proteins - Xencor

Alternative Names: IL-18-Fc

Latest Information Update: 28 May 2026

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At a glance

Originator Xencor
Class Antineoplastics; Immunoglobulin Fc fragments; Immunotherapies; Interleukins; Proteins; Recombinant fusion proteins
Mechanism of Action Immunostimulants; Interleukin 18 replacements

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

28 May 2026 No recent reports of development identified for preclinical development in Cancer in USA
15 Apr 2022 Pharmacodynamics data from a preclinical trial in Cancer presented at the (full name of conference 113th Annual Meeting of the American Association for Cancer Research (AACR-2022) (Xencor website, April 2022)
08 Apr 2022 Preclinical trials in Cancer in USA

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