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SPC 15

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Drug Profile

SPC 15

Alternative Names: SPC-15

Latest Information Update: 13 Nov 2025

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At a glance

  • Originator Columbia University
  • Developer Silo Pharma
  • Class Antidepressants; Anxiolytics
  • Mechanism of Action Serotonin 4 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Preclinical Anxiety disorders; Post-traumatic stress disorders

Most Recent Events

  • 23 Oct 2025 Silo expected to conduct meeting with US FDA to confirm the final data points needed to open an IND before year-end in Post-traumatic stress disorders in November 2025
  • 23 Oct 2025 Silo Pharma plans to submit IND to US FDA for Post-traumatic stress disorder and Anxiety disorders in 2026 (Intranasal).
  • 09 Sep 2025 Columbia University has patent protection for prophylactic efficacy of serotonin 4 receptor agonists against stress in Japan

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