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KRRO 110pla

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Drug Profile

KRRO 110pla

Alternative Names: KRRO-110

Latest Information Update: 24 May 2024

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At a glance

  • Originator Korro Bio
  • Class Oligonucleotides
  • Mechanism of Action Alpha 1-antitrypsin modulators; RNA modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Alpha 1-antitrypsin deficiency

Most Recent Events

  • 20 May 2024 Updated pharmacodynamics data from a preclinical trial in Alpha-1 antitrypsin deficiency released by Korro Bio
  • 23 Apr 2024 Korro Bio plans a phase I/II trial for Alpha-1 antitrypsin deficiency
  • 18 Apr 2024 Korro Bio announced the intention to submit regulatory filing for First-in-Human (FIH) study of KRRO 110 in Alpha-1 antitrypsin deficiency (AATD) patients in the second half of 2024

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