Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

KRRO 110

Next Previous
Drug Profile

KRRO 110

Alternative Names: KRRO-110

Latest Information Update: 03 May 2026

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Korro Bio
  • Class Amines; Amino sugars; Drug conjugates; Hepatoprotectants; Oligonucleotides; Pyrrolidines
  • Mechanism of Action Alpha 1-antitrypsin modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Alpha 1-antitrypsin deficiency
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Alpha 1-antitrypsin deficiency

Most Recent Events

  • 17 Apr 2026 Korro Bio terminates a phase I/IIa trial in Alpha 1-antitrypsin deficiency in Australia and New Zealand due business decision reasons (IV) (NCT06677307)
  • 19 Nov 2025 KRRO 110 receives Fast Track designation for Alpha 1-antitrypsin deficiency [IV,Infusion] in USA, prior to November 2025
  • 12 Nov 2025 Adverse events, pharmacokinetics and pharmacokinetics data from the phase I/IIa REWRITE trial in Alpha-1 antitrypsin deficiency released by Korro Bio

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top