Drug Profile

XmAb 412

Alternative Names: TL1A x IL-23 bispecific antibody - Xencor; TL1A x IL23p19 - Xencor; XmAb TL1A x IL-23 bispecific antibody - Xencor; XmAb-412

Latest Information Update: 13 Aug 2026

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At a glance

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

13 Jul 2026 Phase-I clinical trials in Inflammatory bowel diseases (In volunteers) in Australia (IV) (NCT07713485)
13 Jul 2026 Phase-I clinical trials in Inflammatory bowel diseases (In volunteers) in Australia (SC) (NCT07713485)
06 May 2026 Xencor plans a phase I first-in-human trial for Inflammatory bowel diseases (Parenteral) in third quarter of 2026

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