Drug Profile

GB 18

Alternative Names: GB-18

Latest Information Update: 17 Jun 2026

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At a glance

Originator Kexing Biopharm
Class Immunoglobulin Fc fragments; Monoclonal antibodies
Mechanism of Action Growth differentiation factor 15 inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Cachexia

Most Recent Events

10 Jun 2026 Phase-I clinical trials in Cachexia (Inoperable/Unresectable, Late-stage disease, Recurrent, Metastatic disease, Second-line therapy or greater) in China (SC) (NCT07519564)
28 Oct 2025 Phase-I clinical trials in Cachexia (In volunteers) in China (SC) (NCT07237464)
14 Feb 2025 Kexing Biopharm intends to submit an IND application for Cachexia in China, within 2025

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