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PF 08052667

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Drug Profile

PF 08052667

Alternative Names: PF-08052667; SGN-B6N

Latest Information Update: 17 Nov 2025

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At a glance

  • Originator Seagen
  • Developer Pfizer
  • Class Antibodies; Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Bladder cancer

Most Recent Events

  • 20 Oct 2025 Phase-I clinical trials in Bladder cancer (Combination therapy, Recurrent) in USA (Intravesicular) (NCT07206225)
  • 20 Oct 2025 Phase-I clinical trials in Bladder cancer (Monotherapy, Recurrent) in USA (Intravesicular) (NCT07206225)
  • 17 Oct 2025 Adverse events, pharmacokinetics, pharmacodynamics data from preclinical trials in Bladder cancer presented at the 50th European Society for Medical Oncology Congress (ESMO-2025)

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