Drug Profile

DII 235

Alternative Names: BW-20829; DII-235

Latest Information Update: 03 Feb 2026

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At a glance

Originator Argo Biopharma
Developer Novartis
Class Antihyperlipidaemics; Small interfering RNA
Mechanism of Action Gene silencing; Lipoprotein A expression inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Hyperlipoproteinaemia

Most Recent Events

25 Jan 2026 DII 235 licensed to Novartis worldwide
02 Dec 2025 Phase-II clinical trials in Hyperlipoproteinaemia in Japan, USA (SC) (NCT07235046)
19 Nov 2025 Preclinical trials in Hyperlipoproteinaemia in USA (Parenteral), prior to November 2025

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