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A double-blind, placebo-controlled evaluation of the safety and efficacy of RGH-188 [cariprazine] in the acute exacerbation of schizophrenia

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Trial Profile

A double-blind, placebo-controlled evaluation of the safety and efficacy of RGH-188 [cariprazine] in the acute exacerbation of schizophrenia

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 24 Aug 2021

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At a glance

  • Drugs Cariprazine (Primary)
  • Indications Schizophrenia
  • Focus Proof of concept; Therapeutic Use
  • Sponsors Forest Laboratories
  • Most Recent Events

    • 30 Jun 2021 Results of post -hoc analysis from NCT00404573, NCT01104779, NCT00694707, NCT01104766, NCT01104792, NCT00839852, NCT01412060, EudraCT 2012-005485-36 assessing safety Profile of Cariprazine and Potential Relevance for Patient Adherence in Schizophrenia presented at the 15th World Congress of Biological Psychiatry
    • 15 Sep 2020 Results of pooled post hoc analysis from NCT00404573, NCT01104766, NCT01104779, NCT00694707 assessing efficacy of cariprazine in the approved dose range versus placebo for reducing agitation and hostility in adult patients with an acute exacerbation of schizophrenia, presented at the 33rd Annual Congress of the European College of Neuropsychopharmacology
    • 20 Sep 2016 Post hoc pooled analysis results of this (NCT00404573) and other trials (NCT01058096, NCT00694707, NCT00488618, NCT01104766, NCT01058668, NCT01104779) presented at the 29th Annual Congress of the European College of Neuropsychopharmacology

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