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A study of ARQ 197 in healthy volunteers to assess the pharmacokinetic (PK) profile in extensive and poor metabolizers as defined by cytochrome P450 2c19 (CYP [cytochrome] 2C19) genotype

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Trial Profile

A study of ARQ 197 in healthy volunteers to assess the pharmacokinetic (PK) profile in extensive and poor metabolizers as defined by cytochrome P450 2c19 (CYP [cytochrome] 2C19) genotype

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 13 Dec 2023

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At a glance

  • Drugs Tivantinib (Primary)
  • Indications Colorectal cancer; Gastric cancer; Germ cell cancer; Liver cancer; Non-small cell lung cancer; Pancreatic cancer; Renal cancer; Soft tissue sarcoma; Solid tumours
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors ArQule

Most Recent Events

  • 21 Jun 2008 Status changed from recruiting to completed, as reported by ClinicalTrials.gov.
  • 21 Jun 2008 The expected completion date for this trial is now 1 Jun 2008.
  • 22 Apr 2008 New trial record.

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