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A Phase I/II, Open Label Study to Evaluate Safety, Tolerability and Therapeutic Effects of Transplantation of Autologous Cultured Mesenchymal Bone Marrow Stromal Cells Secreting Neurotrophic Factors (MSC-NTF), in ALS Patients.

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Trial Profile

A Phase I/II, Open Label Study to Evaluate Safety, Tolerability and Therapeutic Effects of Transplantation of Autologous Cultured Mesenchymal Bone Marrow Stromal Cells Secreting Neurotrophic Factors (MSC-NTF), in ALS Patients.

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 17 Jan 2019

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At a glance

  • Drugs Debamestrocel (Primary) ; Debamestrocel (Primary)
  • Indications Amyotrophic lateral sclerosis
  • Focus Adverse reactions; First in man
  • Sponsors Brainstorm Cell Therapeutics

    • Most Recent Events

    • 10 May 2016 According to a BrainStorm Cell Therapeutics media release, combined results from this and a phase IIa trial (CTP 700228777) were presented at the ISRASTEM 2016 and 6th Israel Stem Cell Society (ISCS) joint annual meeting.
    • 29 Mar 2016 According to a BrainStorm media release, combined results from this and a phase IIa trial (CTP 700228777) will be presented at the ISRASTEM 2016 and the 6th International Israel Stem Cell Society Joint Annual Meeting
    • 11 Jan 2016 Combined results of this and a phase IIa trial (CTP 700228777) published in the JAMA Neurology, according to a BrainStorm Cell Therapeutics media release.

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