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A Phase I, Three-Arm Safety, Tolerability, and Pharmacokinetic Interaction Study of PA-824, an Investigational Nitroimidazole for the Treatment of Tuberculosis, Together With Efavirenz, Ritonavir-Boosted Lopinavir, or Rifampin

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Trial Profile

A Phase I, Three-Arm Safety, Tolerability, and Pharmacokinetic Interaction Study of PA-824, an Investigational Nitroimidazole for the Treatment of Tuberculosis, Together With Efavirenz, Ritonavir-Boosted Lopinavir, or Rifampin

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 01 Dec 2020

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At a glance

  • Drugs Pretomanid (Primary) ; Efavirenz; Lopinavir/ritonavir; Rifampicin
  • Indications HIV infections; Tuberculosis
  • Focus Adverse reactions; Pharmacokinetics
  • Most Recent Events

    • 23 Nov 2020 Results (n=32) published in the Antimicrobial Agents and Chemotherapy
    • 06 May 2013 Planned End Date (Jun 2013) added as reported by ClinicalTrials.gov.
    • 01 May 2013 Status changed from recruiting to completed as reported by ClinicalTrials.gov.

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