A Phase I Trial of MEK Inhibitor Trametinib in Combination With Neoadjuvant 5-Fluorouracil Chemoradiation in the Treatment of KRAS, BRAF, and NRAS-MUTANT Rectal Cancers
Latest Information Update: 20 Sep 2023
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At a glance
- Drugs Trametinib (Primary) ; Fluorouracil; Folinic acid; Oxaliplatin
- Indications Adenocarcinoma; Rectal cancer
- Focus Adverse reactions
- 14 Sep 2023 Status changed from active, no longer recruiting to completed.
- 24 Nov 2020 Planned primary completion date changed from 31 Dec 2017 to 31 Dec 2021.
- 06 Apr 2020 Results published in the Clinical Cancer Research