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An Open Label, Single Centre, Phase II Pilot Study of Neoadjuvant Dabrafenib + Trametinib in Patients With Resectable American Joint Committee on Cancer (AJCC) Stage IIIB-C BRAF V600 Mutation Positive Melanoma (Neo Combi)

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Trial Profile

An Open Label, Single Centre, Phase II Pilot Study of Neoadjuvant Dabrafenib + Trametinib in Patients With Resectable American Joint Committee on Cancer (AJCC) Stage IIIB-C BRAF V600 Mutation Positive Melanoma (Neo Combi)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 14 Jul 2022

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At a glance

  • Drugs Dabrafenib (Primary) ; Trametinib (Primary)
  • Indications Malignant melanoma
  • Focus Therapeutic Use
  • Acronyms Neo Combi

    • Most Recent Events

    • 12 Jul 2022 Planned End Date changed from 1 May 2022 to 1 May 2024.
    • 07 Jun 2022 Status changed from active, no longer recruiting to completed, according to Results presented at the 58th Annual Meeting of the American Society of Clinical Oncology.
    • 07 Jun 2022 Results assessing 5-year outcomes were presented at the 58th Annual Meeting of the American Society of Clinical Oncology.

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