Trial Profile

A Dual Phase 1/2, Investigator Initiated Study to Determine the Maximum Tolerated Dose, Safety, and Efficacy of 186Rhenium Nanoliposomes (186RNL) in Recurrent Glioma (CTRC 12-02)

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 31 Mar 2025

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At a glance

Drugs Rhenium (186Re) obisbemeda (Primary)
Indications Astrocytoma; Diffuse intrinsic pontine glioma; Ependymoma; Glioblastoma; Glioma
Focus Adverse reactions; First in man; Registrational; Therapeutic Use
Acronyms ReSPECT; ReSPECT-GBM; ReSPECT-TM
Sponsors Plus Therapeutics

Most Recent Events

26 Mar 2025 Planned End Date changed from 1 Jan 2025 to 1 Dec 2025.
26 Mar 2025 Planned primary completion date changed from 1 Jan 2025 to 1 Dec 2025.
07 Mar 2025 According to the Plus Therapeutics Media Release, the company announced the publication in the peer-reviewed medical journal Nature Communications.

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