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A Phase IIa Study of the MEK Inhibitor GSK1120212 Monotherapy in the Treatment of Gemcitabine Refractory Locally Advanced, Recurrent or Metastatic Biliary Tract Cancers

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Trial Profile

A Phase IIa Study of the MEK Inhibitor GSK1120212 Monotherapy in the Treatment of Gemcitabine Refractory Locally Advanced, Recurrent or Metastatic Biliary Tract Cancers

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 22 Aug 2023

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At a glance

  • Drugs Trametinib (Primary)
  • Indications Biliary cancer
  • Focus Proof of concept; Therapeutic Use
  • Sponsors GlaxoSmithKline; GSK

    • Most Recent Events

    • 01 Jan 2018 Primary endpoint of non-PD rate (Assessed by Independent Radiologist) has not been met, as per results published in the Cancer Science
    • 01 Jan 2018 Primary endpoint of non-PD rate (Assessed by Investigator) has not been met, as per results published in the Cancer Science
    • 01 Jan 2018 Results published in the Cancer Science

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