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A Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery Requiring Cardiopulmonary Bypass

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Trial Profile

A Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery Requiring Cardiopulmonary Bypass

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 16 Mar 2022

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At a glance

  • Drugs Levosimendan (Primary)
  • Indications Low cardiac output
  • Focus Registrational; Therapeutic Use
  • Acronyms LEVO-CTS
  • Sponsors Tenax Therapeutics

    • Most Recent Events

    • 06 Mar 2022 Results describing variables and outcomes associated with peri-operative mechanical circulatory support utilization among patients enrolled in the Levosimendan in patients with Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery, published in the American Heart Journal
    • 27 Oct 2020 Results (n=854) of post hoc analysis assessing association between levosimendan, postoperative AKI, and mortality in cardiac surgery published in the American Heart Journal
    • 18 Nov 2019 Results (n=854) assessing clinical outcomes compared between patients with and without AKI were presented at the American Heart Association Scientific Sessions 2019

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