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A Phase III, Open-label, Extension Trial of ECU-NMO-301 to Evaluate the Safety and Efficacy of Eculizumab in Patients With Relapsing Neuromyelitis Optica (NMO)

Trial Profile

A Phase III, Open-label, Extension Trial of ECU-NMO-301 to Evaluate the Safety and Efficacy of Eculizumab in Patients With Relapsing Neuromyelitis Optica (NMO)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Nov 2023

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At a glance

  • Drugs Eculizumab (Primary)
  • Indications Neuromyelitis optica
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Sponsors Alexion AstraZeneca Rare Disease

Most Recent Events

  • 28 Jun 2022 Results reporting long term relapse-risk-reduction efficacy and safety data from two clinical studies: PREVENT (NCT01892345) and its OLE (NCT02003144) presented at the 8th Congress of the European Academy of Neurology
  • 06 Apr 2022 Status changed from active, no longer recruiting to completed.
  • 01 Mar 2022 Results from PREVENT and its open-label extension study (NCT01892345, NCT02003144) published in the Multiple Sclerosis Journal

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