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Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMS-986165 in Healthy Subjects and to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Efficacy of BMS-986165 in Subjects With Moderate to Severe Psoriasis

Trial Profile

Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMS-986165 in Healthy Subjects and to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Efficacy of BMS-986165 in Subjects With Moderate to Severe Psoriasis

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Deucravacitinib (Primary) ; Famotidine; Interferon alpha-2a; Ustekinumab
  • Indications Plaque psoriasis
  • Focus Adverse reactions; First in man
  • Sponsors Bristol-Myers Squibb
  • Most Recent Events

    • 17 Jun 2017 Results assessing safety, pharmacokinetics, and pharmacodynamics of BMS-986165 in healthy volunteers (n=108), presented at the 18th Annual Congress of the European League Against Rheumatism
    • 14 Jun 2017 According to a Bristol-Myers Squibb media release, data will be presented at the Annual European Congress of Rheumatology (EULAR 2017)
    • 02 Dec 2016 Status changed from recruiting to completed.

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