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A Phase 1b, Multicenter, Open-label Study of Acalabrutinib in Combination With Bendamustine and Rituximab (BR) or Venetoclax and Rituximab (VR) in Subjects With Mantle Cell Lymphoma

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Trial Profile

A Phase 1b, Multicenter, Open-label Study of Acalabrutinib in Combination With Bendamustine and Rituximab (BR) or Venetoclax and Rituximab (VR) in Subjects With Mantle Cell Lymphoma

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 26 Nov 2024

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At a glance

  • Drugs Acalabrutinib (Primary) ; Bendamustine; Rituximab; Venetoclax
  • Indications Mantle-cell lymphoma
  • Focus Adverse reactions
  • Sponsors Acerta Pharma
  • Most Recent Events

    • 08 Aug 2023 Planned End Date changed from 20 Jun 2027 to 20 Aug 2027.
    • 15 Jun 2023 Updated results (n=38) assessing safety and efficacy of triple combination ABR in patients with TN or R/R MCL presented at the 28th Congress of the European Haematology Association
    • 06 Jun 2023 Results (n=38; as of data cutoff: 15 Jun 22) reporting updated data on safety and efficacy of ABR in patients with TN or R/R MCL presented at the 59th Annual Meeting of the American Society of Clinical Oncology

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