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Phase 1a, Randomized, Double-blinded, Placebo-controlled, Single-dose Escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetics of ELX-02 in Healthy Adult Volunteers

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Trial Profile

Phase 1a, Randomized, Double-blinded, Placebo-controlled, Single-dose Escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetics of ELX-02 in Healthy Adult Volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 15 Mar 2019

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At a glance

  • Drugs Exaluren (Primary) ; Exaluren (Primary)
  • Indications Cystic fibrosis; Cystinosis; Duchenne muscular dystrophy; Inborn genetic disorders; Mucopolysaccharidosis I; Rett syndrome
  • Focus Adverse reactions; First in man
  • Sponsors Eloxx Pharmaceuticals

    • Most Recent Events

    • 08 Mar 2019 According to an Eloxx Pharmaceuticals media release, results from phase 1a single-ascending dose (SAD) study for ELX-02 (NCT02807961 and NCT03292302) have been published in the January 2019 edition of the Journal of Clinical Pharmacology and Drug Development.
    • 08 Nov 2018 According to an Eloxx Pharmaceutical media release, the results have been submitted to a scientific journal for publication.
    • 19 Mar 2018 According to an Eloxx Pharmaceutical media release, results from the completed Phase 1 SAD study (NCT02807961 and NCT03292302) will be included in the planned IND and CTA submissions.

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