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A Prospective, Randomized, Double-Blinded, Placebo-Controlled, Multinational, Multicenter, Parallel-group, Phase III Study to Evaluate the Efficacy and Safety of Apatinib Plus Best Supportive Care (BSC) Compared to Placebo Plus BSC in Patients With Advanced or Metastatic Gastric Cancer

Trial Profile

A Prospective, Randomized, Double-Blinded, Placebo-Controlled, Multinational, Multicenter, Parallel-group, Phase III Study to Evaluate the Efficacy and Safety of Apatinib Plus Best Supportive Care (BSC) Compared to Placebo Plus BSC in Patients With Advanced or Metastatic Gastric Cancer

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 11 Jul 2022

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At a glance

  • Drugs Rivoceranib (Primary)
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms ANGEL
  • Sponsors Elevar Therapeutics; LSK Biopharma

Most Recent Events

  • 10 Oct 2020 This trial has been completed in Germany, Poland and France.
  • 22 Jun 2020 Planned End Date changed from 31 Mar 2019 to 31 Jul 2020.
  • 09 Mar 2020 According to an Elevar Therapeutics media release, the company is in discussions with the FDA to receive advice on regulatory submissions for monotherapy gastric cancer treatment.

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