Study to Evaluate the Safety, Tolerability, Preliminary Efficacy and Pharmacokinetics of Simmitecan and Simmitecan, 5-fluorouracil and Leucovorin Calcium, in Patients With Advanced Solid Tumors
Latest Information Update: 05 Nov 2021
At a glance
- Drugs Simmitecan (Primary) ; Fluorouracil; Folinic acid; Thalidomide
- Indications Biliary cancer; Carcinoma; Colorectal cancer; Gallbladder cancer; Gastric cancer; Gastrointestinal cancer; Gastrointestinal stromal tumours; Liver cancer; Neuroendocrine carcinoma; Oesophageal cancer; Pancreatic cancer; Solid tumours
- Focus Pharmacokinetics
- Sponsors Haihe Biopharma; ShangHai HaiHe Pharmaceutical
- 31 May 2020 Results (n=41) assessing safety and efficacy presented at the 56th Annual Meeting of the American Society of Clinical Oncology
- 18 Jul 2017 Number of arms of the study has increased from 4 to 6,hence number of planned patient number has also changed from 153 to243.
- 11 Jul 2017 Planned number of patients changed from 158 to 243.