A Phase II Study of the TRIplet Combination of Dabrafenib, Nivolumab, and Trametinib in Patients With Metastatic Melanoma (TRIDeNT) or Binimetinib, EnCorafenib, and NivolumAb (TRIBECA))
Latest Information Update: 13 Jan 2026
At a glance
- Drugs Binimetinib (Primary) ; Dabrafenib (Primary) ; Encorafenib (Primary) ; Nivolumab (Primary) ; Trametinib (Primary)
- Indications Brain metastases; Malignant melanoma
- Focus Therapeutic Use
Most Recent Events
- 17 Dec 2025 Planned End Date changed from 8 Dec 2025 to 8 Dec 2027.
- 17 Dec 2025 Planned primary completion date changed from 8 Dec 2025 to 8 Dec 2027.
- 09 Oct 2024 Planned End Date changed from 8 Dec 2024 to 8 Dec 2025.