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A Multicenter Phase II Trial of Pemetrexed Plus Carboplatin With or Without Apatinib in Patients With Advanced Non-small Cell Lung Cancer Without EGFR Mutation, ALK Gene Rearrangement, and ROS1 Gene Rearrangement

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A Multicenter Phase II Trial of Pemetrexed Plus Carboplatin With or Without Apatinib in Patients With Advanced Non-small Cell Lung Cancer Without EGFR Mutation, ALK Gene Rearrangement, and ROS1 Gene Rearrangement

Status: Withdrawn prior to enrolment
Phase of Trial: Phase II

Latest Information Update: 12 Dec 2024

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At a glance

  • Drugs Rivoceranib (Primary) ; Carboplatin; Pemetrexed
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms APPEAL

    • Most Recent Events

    • 10 Dec 2024 Status changed to withdrawn prior to enrolment.
    • 04 Sep 2024 Planned End Date changed from 20 May 2020 to 20 May 2027.
    • 04 Sep 2024 Planned primary completion date changed from 20 May 2019 to 20 May 2025.

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