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NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of LOXO-101 (Larotrectinib) in Patients With Tumors Harboring Actionable NTRK Fusions

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NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of LOXO-101 (Larotrectinib) in Patients With Tumors Harboring Actionable NTRK Fusions

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 16 Nov 2024

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At a glance

  • Drugs Larotrectinib (Primary) ; Larotrectinib (Primary)
  • Indications CNS cancer; Ependymoma; Ewing's sarcoma; Germ cell and embryonal neoplasms; Germ cell cancer; Glioma; Langerhans cell histiocytosis; Medulloblastoma; Neuroblastoma; Non-Hodgkin's lymphoma; Osteosarcoma; Rhabdoid tumour; Rhabdomyosarcoma; Soft tissue sarcoma; Solid tumours; Wilms' tumour
  • Focus Therapeutic Use
  • Acronyms Pediatric MATCH

    • Most Recent Events

    • 10 Oct 2024 Planned End Date changed from 30 Sep 2024 to 8 Oct 2025.
    • 02 Jan 2024 Status changed from recruiting to active, no longer recruiting.
    • 09 Apr 2018 Planned End Date changed from 31 Mar 2022 to 30 Sep 2024.

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